Francis Bursa

About Francis Bursa

Senior Statistician – Francis joined Quantics in 2013. With a Masters from Cambridge and DPhil in Theoretical Physics from Oxford University, Francis brings high level mathematical ability and extensive experience in simulation techniques to Quantics. These techniques can be used to explore “what if” scenarios, reducing the need for further experimental data. Francis heads the R&D team.

Complications of fitting 4PL and 5PL models to bioassay data

Welcome to our fourth bioassay blog from Quantics Biostatistics. In our previous blog we discussed the 4 parameter logistic (4PL) model. This is a symmetrical S-shaped curve with... read more →

26th June 2021
Uncategorised

Pseudo-replicates and Bioassay

This blog explains the difference between true replicates and pseudo-replicates, and discusses the problems that may arise if this difference is ignored or misunderstood in bioassay statistical analysis. Quality... read more →

31st January 2020
All Blogs, Bioassay

pseudo-replicates: Pure Error Bioassay 8 doses

When is Pure Error for Bioassay an Error?

Software systems for calculating relative potencies and other bioanalytical results often provide a choice of variance estimation method, usually: Residuals, Lack of fit Error and Pure Error. This defines... read more →

6th September 2019
All Blogs, Bioassay

How to Set Suitability Criteria for Relative Potency Bioassays

We previously discussed the purpose of system suitability tests and sample suitability tests and gave some examples of each. However, we did not explain how to actually set the limits... read more →

15th February 2019
All Blogs, Bioassay

Suitability Tests for Bioassay

Suitability tests for bioassay are often confusing. In this blog, we discuss the two types of suitability tests: System suitability tests and Sample suitability tests. The blog is deliberately... read more →

31st August 2018
All Blogs, Bioassay

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