Slide keyboard_arrow_down QuBAS is a feature rich statistical analysis software package with all of the commonly used statistical methods for relative potency and ELISA assays.

Slide Probit Probit Slide Logit Logit Slide Linea Linear Models Slide 5PL 5PL Models Slide 4pl 4PL Models Slide Equivalence Tests Equivalence Tests Slide 4pl Interpolation Slide cancel Outlier Management Slide GMP and 21 CFR Compliant Slide picture_as_pdf PDF Reports Slide Transform Dose & Response Slide Graphical Plate Template All the features you'd expect...

Slide autorenew Auto-import and export Slide Unlimited meta-data trending Slide Continuous real-time Validation Slide Minimal training & no formulae required Slide Interactive record of development Slide Access from anywhere Slide Language settings Slide Intuitive allocation view Slide contact_support Statistical support from Quantics Slide swap_calls Maximum flexibility Slide business_center Developer's Toolbox ...and so much more.
plate map relative potency

QuBAS Bioassay Software

QuBAS is a feature rich statistical analysis software package with all of the commonly used statistical methods for relative potency and ELISA assays.

QuBAS has a highly intuitive graphical user interface allowing very rapid analysis method design.

Slide From Plate Reader to GMP Analysis Report & directly into your LIMS in one click.

QuBAS can be set to automatically import from a pre-specified folder location on your server. When data files are saved to this folder from your plate reader, the file will be automatically imported into QuBAS and the appropriate Routine Method run with no user input and then exported into your LIMS. An unlimited amount of routine methods can be set to watch different folders freeing up lots of QC time for other things.
Auto-Import & Auto-Export

GMP, 21 CFR part 11 compliance

QuBAS is 21 CFR part 11  and GMP compliant with 2 stage electronic signatures for locked down routine GMP analysis, and for reports.

Quantics have provided all the statistical functions and system and sample suitability tests required for US and European regulatory submissions, all pre programmed and selectable by simple drop down menus and drag and drop functions. No user programming is required,  greatly reducing the QA time associated with checking the analysis parameters are correct.

Simple to use.

Simple to use, requiring little training

QuBAS is very simple to use. It is set up as an internal website on your company’s server systems, and accessed using a  Chrome or Firefox browser. It looks and feels like a modern App.

It is highly structured and intuitive, and very little training is required to be able to use all the functionality.

Automatic trending of all data

All results in the Development record, and all results run in the “Routine” locked GMP mode are automatically available in the monitoring room. An outlying point can be explored and the original full assay report for that analysis downloaded directly from the trend graph.

The results can be trended against time, but also against any other metadata that has been collected, such as operator ID, or critical reagent  lot number. In this example, there appear to be 2 distinct groups of relative potency results. Changing the trend plot to show operator indicates that this is not the cause of the problem. Changing again to show critical reagent batch number reveals batch 002 as the issue.

Monitoring Room

Slide QuBAS is installed on your company’s server system, and can be accessed from any computer on the company network using Chrome or FireFox browser. It can also be accessed from anywhere in the world over a VPN link to your company’s server.

Not only does this mean that there is no local installation that requires GMP control or IT maintenance, it also opens the possibility of pharma companies providing a VPN link to contract manufacturers so that all data analysis is done on the pharma companies QuBAS systems, and is thus accessible and visible at all times.
No Local Desktop Installation

Diverse self-checking pair programming CrtV™

The QuBAS QA and QC system is based on the same underlying computer technology as the AirBUS A350 aircraft (CrtV) which means no user validation process is required, even for GxP work. Each analysis report is created with its own full audit trail and real time validation record. CrtV was originally developed by Quantics for in house use for GxP analysis. The MHRA inspection auditor described the process as “innovative and elegant” and fully accepted that traditional IQ, OQ, PQ is not required with this process. Results are 100% QCd by QuBAS using Diverse Self Checking Pair Programing (DSCPP).

AirBus

The CrtV Automated Process

QuBAS uses a unique system of CrtV which means no user validation process is required, even for GxP work. Each analysis report is created with its own full audit trail and real time validation record. 

CrtV was originally developed by Quantics for in house GxP analysis. The MHRA inspection auditor described the process as “innovative and elegant” and fully accepted that traditional IQ, OQ, PQ is not required with this process.

Results are 100% QC’ed by QuBAS using Diverse Self Checking Pair Programming (DSCPP), part of our CrtV method.

Slide All data is stored and checked against encrypted hash checksums.

This animation demonstrates how QuBAS uses checksums. When data is stored to the database, a checksum is created, encrypted, then stored in a separate part of the database. When the data is retrieved from the database, a new checksum is created, the original is retrieved and de-cripted, and the two are compared. If they are identical, the data can be used. If not, then the data has been changed and a data integrity error is reported.

Within QuBAS this process occurs for every data item stored – all numbers all results, all text elements and audit trail elements. QuBAS guarantees that altered data will not go unnoticed.
Optimal Data Integrity Management

Dear QuBAS customers,

You may be aware that an important software vulnerability with the popular Java library ‘log4j’ has recently been discovered.

We want to assure our clients and users that QuBAS and its plugins are not written in Java and thus are not affected by this issue.