Slide keyboard_arrow_down QuBAS is a feature rich statistical analysis software package with all of the commonly used statistical methods for relative potency and ELISA assays.

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Slide Probit Probit All the features you'd expect...

Slide autorenew Auto-import and export Slide Unlimited meta-data trending Slide Continuous real-time Validation Slide Minimal training & no formulae required Slide Interactive record of development Slide Access from anywhere Slide Language settings Slide Intuitive allocation view Slide contact_support Statistical support from Quantics Slide swap_calls Maximum flexibility Slide business_center Developer's Toolbox ...and so much more.
Quantics is pleased to announce that the newest version of our bioassay software, QuBAS 3.0 is now available. 
Our brand new ‘Developer’ room, makes QuBAS Version 3.0 our most flexible piece of software yet – ideal for early-stage development. 
QuBAS 3.0 can revolutionise your analysis.

Developer’s Toolbox

Supporting you in your development, QuBAS 3.0 has all the tools you need to build your analysis – your way. 

Maximum flexibility

  1. Simply start with a data set
  2. Highlight the information QuBAS needs, just a single set of doses and responses will do;
  3. Select an analysis – get a quick fit dose response curve;
  4. Build in more as development proceeds – a reference sample, QC samples, control wells, ID information other meta-data, system and sample suitability criteria. 

Statistical support from Quantics

Since 2002, Quantics has provided expert statistical consultancy for the life science, pharmaceutical and medical device industries. With Quantics, you can have 100% confidence that your statistics are robust.

Intuitive view of allocation

Complicated data / plate layout? Switch to View and QuBAS will reorganise all information into simple tabular form.

Auto-import and export

QuBAS 3.0 can be set to automatically import from a pre-specified folder location on your server. When data files are saved to this folder from your plate reader, the file will be imported automatically into QuBAS and the appropriate analysis run without user input. The report is exported as a .pdf file as well as a variety of formats suitable for LIMS, all compliant with 21 CFR pt11, GMP.   

IT-friendly: with access from anywhere

QuBAS is set up as an internal website and accessed using a Chrome or Firefox browser from any device on your network. It can also be accessed from anywhere in the world over a VPN link to the company’s server. Not only does this mean that there is no local installation that requires GMP control or IT maintenance, it also opens the possibility of providing a VPN link to your contract manufacturers so that all data analysis is accessible and visible at all times.

Interactive record
of development

The record of development is an interactive record of key analyses and design layouts. 

Key (milestones) during the development phase are captured and the report can be exported for inclusion in the assay record of development for submission.

Slide From Plate Reader to GMP Analysis Report & directly into your LIMS in one click.

QuBAS can be set to automatically import from a pre-specified folder location on your server. When data files are saved to this folder from your plate reader, the file will be automatically imported into QuBAS and the appropriate Routine Method run with no user input and then exported into your LIMS. An unlimited amount of routine methods can be set to watch different folders freeing up lots of QC time for other things.
Auto-Import & Auto-Export

GMP, 21 CFR part 11 compliance

QuBAS is 21 CFR part 11  and GMP compliant with 2 stage electronic signatures for locked down routine GMP analysis, and for reports.

Quantics have provided all the statistical functions and system and sample suitability tests required for US and European regulatory submissions, all pre programmed and selectable by simple drop down menus and drag and drop functions. No user programming is required,  greatly reducing the QA time associated with checking the analysis parameters are correct.

Simple to use.

Simple to use, requiring little training

QuBAS is very simple to use. It is set up as an internal website on your company’s server systems, and accessed using a  Chrome or Firefox browser. It looks and feels like a modern App.

It is highly structured and intuitive, and very little training is required to be able to use all the functionality.

Automatic trending of all data

All results in the Development record, and all results run in the “Routine” locked GMP mode are automatically available in the monitoring room. An outlying point can be explored and the original full assay report for that analysis downloaded directly from the trend graph.

The results can be trended against time, but also against any other metadata that has been collected, such as operator ID, or critical reagent  lot number. In this example, there appear to be 2 distinct groups of relative potency results. Changing the trend plot to show operator indicates that this is not the cause of the problem. Changing again to show critical reagent batch number reveals batch 002 as the issue.

Monitoring Room

Slide QuBAS is installed on your company’s server system, and can be accessed from any computer on the company network using Chrome or FireFox browser. It can also be accessed from anywhere in the world over a VPN link to your company’s server.

Not only does this mean that there is no local installation that requires GMP control or IT maintenance, it also opens the possibility of pharma companies providing a VPN link to contract manufacturers so that all data analysis is done on the pharma companies QuBAS systems, and is thus accessible and visible at all times.
No Local Desktop Installation

Diverse self-checking pair programming CrtV™

The QuBAS QA and QC system is based on the same underlying computer technology as the AirBUS A350 aircraft (CrtV) which means no user validation process is required, even for GxP work. Each analysis report is created with its own full audit trail and real time validation record. CrtV was originally developed by Quantics for in house use for GxP analysis. The MHRA inspection auditor described the process as “innovative and elegant” and fully accepted that traditional IQ, OQ, PQ is not required with this process. Results are 100% QCd by QuBAS using Diverse Self Checking Pair Programing (DSCPP).

AirBus

The CrtV Automated Process

QuBAS uses a unique system of CrtV which means no user validation process is required, even for GxP work. Each analysis report is created with its own full audit trail and real time validation record. 

CrtV was originally developed by Quantics for in house GxP analysis. The MHRA inspection auditor described the process as “innovative and elegant” and fully accepted that traditional IQ, OQ, PQ is not required with this process.

Results are 100% QC’ed by QuBAS using Diverse Self Checking Pair Programming (DSCPP), part of our CrtV method.

Slide All data is stored and checked against encrypted hash checksums.

This animation demonstrates how QuBAS uses checksums. When data is stored to the database, a checksum is created, encrypted, then stored in a separate part of the database. When the data is retrieved from the database, a new checksum is created, the original is retrieved and de-cripted, and the two are compared. If they are identical, the data can be used. If not, then the data has been changed and a data integrity error is reported.

Within QuBAS this process occurs for every data item stored – all numbers all results, all text elements and audit trail elements. QuBAS guarantees that altered data will not go unnoticed.
Optimal Data Integrity Management