In an ideal world, a single randomized controlled trial (RCT) would be used to compare and evaluate the individual treatment effects for all possible treatments of interest. Of course, this... read more →
A standard pairwise meta-analysis can compare the efficacy or safety of exactly two treatments that have been directly compared in head-to-head clinical trials. However, in practice, there are often... read more →
In the context of network meta-analysis, indirect treatment comparison is used to describe the analysis of networks that do not contain any loops What is network meta-analysis? To begin with,... read more →
What do ISS & ISE mean? ISS & ISE stand for integrated summary of safety and integrated summary of effectiveness, respectively. These are not merely summaries, as the... read more →
The Safety Population is used for the analysis of safety, including adverse events, toxicity and laboratory evaluations. A patient should be included if, and only if, they actually received... read more →