A standard pairwise meta-analysis can compare the efficacy or safety of exactly two treatments that have been directly compared in head-to-head clinical trials. However, in practice, there are often... read more →
In the context of network meta-analysis, indirect treatment comparison is used to describe the analysis of networks that do not contain any loops What is network meta-analysis? To begin with,... read more →
What do ISS & ISE mean? ISS & ISE stand for integrated summary of safety and integrated summary of effectiveness, respectively. These are not merely summaries, as the... read more →
The Safety Population is used for the analysis of safety, including adverse events, toxicity and laboratory evaluations. A patient should be included if, and only if, they actually received... read more →
In our previous blog we looked at study populations and the issues that often arise along with the best practices for dealing with them. One of the issues we highlighted... read more →