So, you’re confident that you’ve got a feasible assay with a well-defined dose-response curve. But bioassays, as we all know, are fickle. The observed responses are sensitive to many... read more →
Vaccines are among the most important technological developments in human history. From the earliest attempts to prevent smallpox by variolation to modern mRNA vaccines built without a virus needing... read more →
One of the most frequent topics of discussion on this blog has been the correct and optimal utilisation of different classes of statistical models with bioassay data. Most common... read more →
Bioassays serve as a method of testing a product: does the latest batch of our biologic have an acceptable potency? To do this effectively, we need to ensure that... read more →
In bioassay analyses, there are three statistical models that are commonly fit to dose-response data: the linear model, the 4PL model, and the 5PL model. We’ve examined the properties... read more →