System Suitability Criteria
Controls
Upper and lower limits can be set for the mean or geometric mean of:
a) All control samples
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By groups if present e.g. high, low
Reference standard
Goodness of fit of the model
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If there is more than one replicate at each dose: lack of fit error can be compared with pure error via an F test.
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The level (critical p value) can be chosen by the user.
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If there is only 1 replicate, there is no Goodness of fit estimation.
Parameter values
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The confidence level for the each interval can be chosen by the user (no default setting).
Statistical significance of dose response 
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via a one-sample t test comparing with zero.
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The level (critical p value) can be chosen by the user
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Combination of parameter values
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Limits for the values of the following can be set.
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The range (difference between asymptotes): |
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The midpoint (ED50) of the 5PL : 
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The amount of asymmetry: Ln(
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Equivalence limits for the following can be set:
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Range for the confidence intervals for (no default setting)
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The range (difference between asymptotes): |
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The midpoint (ED50) of the 5PL :
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The amount of asymmetry: Ln(
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The confidence level for the each interval can be chosen by the user (no default setting).
Variability of data
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An upper limit for the variance, σ2Ref, Mean square error (MSE), can be set.
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An upper limit for σRef the root mean square error (RMSE) can be set.
Quality Control
Goodness of fit of the model
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If there is more than one replicate at each dose: lack of fit error can be compared with pure error via an F test.
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The level (critical p value) can be chosen by the user.
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Statistical significance of 
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via a one-sample t test comparing 
with zero.
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The level (critical p value) can be chosen by the user
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Parallelism with reference standard
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Ranges for combinations of QC and reference parameters can be chosen.
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Difference between equivalent parameters:
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(
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(
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(
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(
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(
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Normalised difference between asymptotes
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Equivalence tests for combinations of QC and reference parameters.
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Ranges for the confidence intervals (no default setting) for:
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(
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(
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(
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(
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(
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The confidence level for the each interval can be chosen by the user (no default setting).
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Significance tests for lack of parallelism can be used:
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F test comparing the unconstrained model with the parallel model.
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The level (critical p value) can be chosen by the user.
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χ2 test comparing the unconstrained model with the parallel model.
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The level (critical p value) can be chosen by the user (no default value).
Relative potency of the QC sample, and its confidence interval
(For calculation of these parameters, see here.)-
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Range for the confidence interval for RP (no default setting).
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The confidence level can be chosen by the user (no default setting).
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Precision: The ratio of upper confidence limit to lower confidence limit
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The confidence level can be chosen by the user (no default setting).
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The upper limit for the precision is chosen by the user
, 
, 
can be set.
location of midpoint and asymmetry can be set:
midpoint, asymmetry (no default setting).
